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Glucocorticoid Receptor Modulates EGFR Feedback upon Acquisition of Resistance to Monoclonal Antibodies

Evidences of a crosstalk between Epidermal Growth Factor Receptor (EGFR) and Glucocorticoid Receptor (GR) has been reported, ranging from the modulation of receptor levels or GR mediated transcriptional repression of EGFR target genes, with modifications of epigenetic markers. The present study focu...

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Bibliographic Details
Published in:J Clin Med
Main Authors: Gelfo, Valerio, Pontis, Francesca, Mazzeschi, Martina, Sgarzi, Michela, Mazzarini, Maria, Solmi, Rossella, D’Uva, Gabriele, Lauriola, Mattia
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572202/
https://ncbi.nlm.nih.gov/pubmed/31052457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8050600
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