Determination and pharmacokinetic study of AZD‐3759 in rat plasma by ultra performance liquid chromatography with triple quadrupole mass spectrometer

BACKGROUND: AZD‐3759 is a new, potent, oral, active central nervous system‐penetrant EGFR inhibitor. Despite promising clinical activity among patients pretreated and never treated with EGFR‐tyrosine kinase inhibitors, no time saving pharmacokinetic study method has been reported in an animal model....

詳細記述

保存先:
書誌詳細
出版年:Thorac Cancer
主要な著者: Wu, Qingjun, Hua, Ailian, Sun, Yaoguang, Ma, Chao, Tian, Wenxin, Huang, Chuan, Yu, Hanbo, Jiao, Peng, Wang, Shuanghu, Tong, Hongfeng, Qiu, Weiwen
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons Australia, Ltd 2018
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209780/
https://ncbi.nlm.nih.gov/pubmed/30252204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12843
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料