Inhibition of CBL-B protects from lethal C. albicans sepsis

Fungal infections claim an estimated 1.5 million lives every year. Mechanisms that protect from fungal infections are still elusive. Recognition of fungal pathogens relies on C-type lectin receptors (CLR) and their downstream signaling kinase SYK. Here we report that the E3-ubiquitin-ligase CBL-B co...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Med
Autors principals: Wirnsberger, Gerald, Zwolanek, Florian, Asaoka, Tomoko, Kozieradzki, Ivona, Tortola, Luigi, Wimmer, Reiner A., Kavirayani, Anoop, Fresser, Friedrich, Baier, Gottfried, Langdon, Wallace Y., Ikeda, Fumiyo, Kuchler, Karl, Penninger, Josef M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209141/
https://ncbi.nlm.nih.gov/pubmed/27428901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4134
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars