Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation

TRAF6 (TNF receptor associated factor 6) plays a pivotal role in NFKB activation and macroautphagy/autophagy activation induced by TLR4 (toll like receptor 4) signaling. The objective of this study was to determine the functional role of PRDX1 (peroxiredoxin 1) in NFKB activation and autophagy activ...

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Bibliografiska uppgifter
I publikationen:Autophagy
Huvudupphovsmän: Min, Yoon, Kim, Mi-Jeong, Lee, Sena, Chun, Eunyoung, Lee, Ki-Young
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2018
Ämnen:
Research Paper - Basic Science
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208450/
https://ncbi.nlm.nih.gov/pubmed/29929436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1474995
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