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ZDHHC11 modulates innate immune response to DNA virus by mediating MITA–IRF3 association
MITA is a central adaptor in innate immune responses to DNA viruses. The mechanisms responsible for recruitment of downstream kinase TBK1 and the transcription factor IRF3 to MITA remains enigmatic. Here we identified ZDHHC11, a member of DHHC palmitoyl transferase family, as a positive regulator of...
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| Foilsithe in: | Cell Mol Immunol |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6207569/ https://ncbi.nlm.nih.gov/pubmed/29429998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.146 |
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