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SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA
MITA (also called STING) is a central adaptor protein in innate immune response to cytosolic DNA. Cellular trafficking of MITA from the ER to perinuclear microsomes after DNA virus infection is critical for MITA activation and onset of innate antiviral response. Here we found that SNX8 is a componen...
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| Vydáno v: | PLoS Pathog |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6188873/ https://ncbi.nlm.nih.gov/pubmed/30321235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007336 |
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