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SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes
IFNγ is a cytokine that plays a key role in host defense against intracellular pathogens. In addition to the canonical JAK-STAT1 pathway, IFNγ also activates an IKKβ-mediated noncanonical signaling pathway that is essential for induction of a subset of downstream effector genes. The molecular mechan...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724276/ https://ncbi.nlm.nih.gov/pubmed/29180417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713462114 |
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