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Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

Data from SIV-infected macaques indicate that virus-specific cytotoxic T lymphocytes (CTL) are mostly present in the extrafollicular (EF) compartment of the lymphoid tissue, with reduced homing to the follicular (F) site. This contributes to the majority of the virus being present in the follicle an...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Wodarz, Dominik, Skinner, Pamela J., Levy, David N., Connick, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207320/
https://ncbi.nlm.nih.gov/pubmed/30335747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006461
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