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Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

Data from SIV-infected macaques indicate that virus-specific cytotoxic T lymphocytes (CTL) are mostly present in the extrafollicular (EF) compartment of the lymphoid tissue, with reduced homing to the follicular (F) site. This contributes to the majority of the virus being present in the follicle an...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Wodarz, Dominik, Skinner, Pamela J., Levy, David N., Connick, Elizabeth
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207320/
https://ncbi.nlm.nih.gov/pubmed/30335747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006461
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