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Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

Data from SIV-infected macaques indicate that virus-specific cytotoxic T lymphocytes (CTL) are mostly present in the extrafollicular (EF) compartment of the lymphoid tissue, with reduced homing to the follicular (F) site. This contributes to the majority of the virus being present in the follicle an...

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Publicado en:PLoS Comput Biol
Autores principales: Wodarz, Dominik, Skinner, Pamela J., Levy, David N., Connick, Elizabeth
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207320/
https://ncbi.nlm.nih.gov/pubmed/30335747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006461
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