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Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

Data from SIV-infected macaques indicate that virus-specific cytotoxic T lymphocytes (CTL) are mostly present in the extrafollicular (EF) compartment of the lymphoid tissue, with reduced homing to the follicular (F) site. This contributes to the majority of the virus being present in the follicle an...

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Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Wodarz, Dominik, Skinner, Pamela J., Levy, David N., Connick, Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207320/
https://ncbi.nlm.nih.gov/pubmed/30335747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006461
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