Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

Data from SIV-infected macaques indicate that virus-specific cytotoxic T lymphocytes (CTL) are mostly present in the extrafollicular (EF) compartment of the lymphoid tissue, with reduced homing to the follicular (F) site. This contributes to the majority of the virus being present in the follicle an...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Wodarz, Dominik, Skinner, Pamela J., Levy, David N., Connick, Elizabeth
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207320/
https://ncbi.nlm.nih.gov/pubmed/30335747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006461
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