Mechanism of increased LDL and decreased triglycerides with SGLT2 inhibition

OBJECTIVE: Sodium glucose cotransporter 2 (SGLT2) inhibition in humans leads to increased levels of LDL cholesterol and decreased levels of plasma triglyceride. Recent studies however, have shown this therapy to lower cardiovascular mortality. In this study, we aimed to determine how SGLT2 inhibitio...

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Dettagli Bibliografici
Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Basu, Debapriya, Huggins, Lesley-Ann, Scerbo, Diego, Obunike, Joseph, Mullick, Adam E., Rothenberg, Paul L., Di Prospero, Nicholas A., Eckel, Robert H., Goldberg, Ira J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207215/
https://ncbi.nlm.nih.gov/pubmed/30354257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311339
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