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Mechanism of increased LDL and decreased triglycerides with SGLT2 inhibition

OBJECTIVE: Sodium glucose cotransporter 2 (SGLT2) inhibition in humans leads to increased levels of LDL cholesterol and decreased levels of plasma triglyceride. Recent studies however, have shown this therapy to lower cardiovascular mortality. In this study, we aimed to determine how SGLT2 inhibitio...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Basu, Debapriya, Huggins, Lesley-Ann, Scerbo, Diego, Obunike, Joseph, Mullick, Adam E., Rothenberg, Paul L., Di Prospero, Nicholas A., Eckel, Robert H., Goldberg, Ira J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207215/
https://ncbi.nlm.nih.gov/pubmed/30354257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311339
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