Lipolysis, and not hepatic lipogenesis, is the primary modulator of triglyceride levels in streptozotocin-induced diabetic mice

OBJECTIVE: Diabetic hypertriglyceridemia is thought to be primarily driven by increased hepatic de novo lipogenesis. However, experiments in animal models indicated that insulin deficiency should decrease hepatic de novo lipogenesis and reduce plasma triglyceride levels. APPROACH AND RESULTS: To add...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Willecke, Florian, Scerbo, Diego, Nagareddy, Prabhakara, Obunike, Joseph C, Barrett, Tessa J, Abdillahi, Mariane L., Trent, Chad M., Huggins, Lesley Ann, Fisher, Edward A, Drosatos, Konstantinos, Goldberg, Ira J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270817/
https://ncbi.nlm.nih.gov/pubmed/25395613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304615
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