Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor

RATIONALE: Animal models have been used to explore factors that regulate atherosclerosis. More recently, they have been used to study the factors that promote loss of macrophages and reduction in lesion size after lowering of plasma cholesterol levels. However, current animal models of atheroscleros...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Basu, Debapriya, Hu, Yunying, Huggins, Lesley-Ann, Mullick, Adam E., Graham, Mark J., Wietecha, Tomasz, Barnhart, Shelley, Mogul, Allison, Pfeiffer, Katharina, Zirlik, Andreas, Fisher, Edward A., Bornfeldt, Karin E., Willecke, Florian, Goldberg, Ira J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815899/
https://ncbi.nlm.nih.gov/pubmed/29321129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.311361
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