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The Functional Effect of Repeated Cryopreservation on Transduced CD34(+) Cells from Patients with Thalassemia
Stable gene marking and effective engraftment of gene-modified CD34(+) hematopoietic stem cells is a prerequisite for gene therapy success but may be challenged by the inevitable cryopreservation of the final product prior to extensive quality assurance testing. We investigated the β-globin gene tra...
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| Опубликовано в: : | Hum Gene Ther Methods |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Mary Ann Liebert, Inc., publishers
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6206548/ https://ncbi.nlm.nih.gov/pubmed/30079761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2018.032 |
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