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Optimizing autologous cell grafts to improve stem cell gene therapy

Over the past decade, stem cell gene therapy has achieved unprecedented curative outcomes for several genetic disorders. Despite the unequivocal success, clinical gene therapy still faces challenges. Genetically-engineered hematopoietic stem cells (HSCs) are particularly vulnerable to attenuation of...

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Publicat a:Exp Hematol
Autors principals: Psatha, Nikoletta, Karponi, Garyfalia, Yannaki, Evangelia
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914411/
https://ncbi.nlm.nih.gov/pubmed/27106799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.04.007
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