Hematopoietic Stem Cell Mobilization for Gene Therapy of Adult Patients With Severe β-Thalassemia: Results of Clinical Trials Using G-CSF or Plerixafor in Splenectomized and Nonsplenectomized Subjects

The safety and efficacy of hematopoietic stem cell (HSC) mobilization was investigated in adult splenectomized (SPL) and non-SPL patients with thalassemia major, in two clinical trials, using different mobilization modes: granulocyte-colony-stimulating factor (G-CSF)-alone, G-CSF following pretreatm...

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Autors principals: Yannaki, Evangelia, Papayannopoulou, Thalia, Jonlin, Erica, Zervou, Fani, Karponi, Garyfalia, Xagorari, Angeliki, Becker, Pamela, Psatha, Nikoleta, Batsis, Ioannis, Kaloyannidis, Panayotis, Tahynopoulou, Varvara, Constantinou, Varnavas, Bouinta, Asimina, Kotta, Konstantia, Athanassiadou, Aglaia, Anagnostopoulos, Achilles, Fassas, Athanasios, Stamatoyannopoulos, George
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255592/
https://ncbi.nlm.nih.gov/pubmed/21952171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.195
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