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An N-Glycosylated Form of SERINC5 Is Specifically Incorporated into HIV-1 Virions

SERINC5 is an inhibitor of retroviral infectivity that is counteracted by viral proteins, including HIV-1 Nef. Inhibition of infectivity by SERINC5 is associated with its incorporation into virions. Nef counteracts this inhibition, presumably by removing SERINC5 from sites of virion assembly at the...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Sharma, Shilpi, Lewinski, Mary K., Guatelli, John
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206478/
https://ncbi.nlm.nih.gov/pubmed/30158294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00753-18
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