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Activities of Transmitted/Founder and Chronic Clade B HIV-1 Vpu and a C-Terminal Polymorphism Specifically Affecting Virion Release

Acute HIV-1 infection is characterized by a type I interferon response, resulting in the induction of host restriction factors. HIV-1 has evolved to counteract these factors, and one such adaptation, the ability of Vpu to counteract BST2/tetherin, is associated with the evolution of simian immunodef...

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Autors principals: Jafari, Moein, Guatelli, John, Lewinski, Mary K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993827/
https://ncbi.nlm.nih.gov/pubmed/24574397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03472-13
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