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HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation
HIV-1 Nef, a protein important for the development of AIDS, has well-characterized effects on host membrane trafficking and receptor downregulation. By an unidentified mechanism, Nef increases the intrinsic infectivity of HIV-1 virions in a host-cell-dependent manner. Here we identify the host trans...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861059/ https://ncbi.nlm.nih.gov/pubmed/26416734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15399 |
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