Polymorphisms in Rhesus Macaque Tetherin Are Associated with Differences in Acute Viremia in Simian Immunodeficiency Virus Δnef-Infected Animals

Tetherin (BST-2 or CD317) is an interferon-inducible transmembrane protein that inhibits virus release from infected cells. To determine the extent of sequence variation and the impact of polymorphisms in rhesus macaque tetherin on simian immunodeficiency virus (SIV) infection, tetherin alleles were...

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Veröffentlicht in:J Virol
Hauptverfasser: Janaka, Sanath Kumar, Tavakoli-Tameh, Aidin, Neidermyer, William J., Serra-Moreno, Ruth, Hoxie, James A., Desrosiers, Ronald C., Johnson, R. Paul, Lifson, Jeffrey D., Wolinsky, Steven M., Evans, David T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Genetic Diversity and Evolution
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206476/
https://ncbi.nlm.nih.gov/pubmed/30135127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00542-18
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