Polymorphisms in Rhesus Macaque Tetherin Are Associated with Differences in Acute Viremia in Simian Immunodeficiency Virus Δnef-Infected Animals

Tetherin (BST-2 or CD317) is an interferon-inducible transmembrane protein that inhibits virus release from infected cells. To determine the extent of sequence variation and the impact of polymorphisms in rhesus macaque tetherin on simian immunodeficiency virus (SIV) infection, tetherin alleles were...

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Vydáno v:J Virol
Hlavní autoři: Janaka, Sanath Kumar, Tavakoli-Tameh, Aidin, Neidermyer, William J., Serra-Moreno, Ruth, Hoxie, James A., Desrosiers, Ronald C., Johnson, R. Paul, Lifson, Jeffrey D., Wolinsky, Steven M., Evans, David T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Genetic Diversity and Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206476/
https://ncbi.nlm.nih.gov/pubmed/30135127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00542-18
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