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Protein Phosphatase 1α and Cofilin Regulate Nuclear Translocation of NF-κB and Promote Expression of the Anti-Inflammatory Cytokine Interleukin-10 by T Cells

While several protein serine/threonine kinases control cytokine production by T cells, the roles of serine/threonine phosphatases are largely unexplored. Here, we analyzed the involvement of protein phosphatase 1α (PP1α) in cytokine synthesis following costimulation of primary human T cells. Small i...

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Publicado en:Mol Cell Biol
Autores principales: Wabnitz, Guido H., Kirchgessner, Henning, Jahraus, Beate, Umansky, Ludmila, Shenolikar, Shirish, Samstag, Yvonne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206454/
https://ncbi.nlm.nih.gov/pubmed/30181394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00041-18
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