An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments

T cells infiltrate peripheral tissues to execute immunosurveillance and effector functions. For this purpose, T cells first migrate on the two-dimensional (2D) surface of endothelial cells to undergo transendothelial migration. Then they change their mode of movement to undergo migration within the...

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Bibliographic Details
Main Authors: Klemke, Martin, Kramer, Elisabeth, Konstandin, Mathias H, Wabnitz, Guido H, Samstag, Yvonne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944044/
https://ncbi.nlm.nih.gov/pubmed/20676060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.153
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