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A comprehensive overview of FCGR3A gene variability by full-length gene sequencing including the identification of V158F polymorphism
The FCGR3A gene encodes for the receptor important for antibody-dependent natural killer cell-mediated cytotoxicity. FCGR3A gene polymorphisms could affect the success of monoclonal antibody therapy. Although polymorphisms, such as the FcγRIIIA-V158F and -48L/R/H, have been studied extensively, an o...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6206037/ https://ncbi.nlm.nih.gov/pubmed/30374078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34258-1 |
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