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CRISPR/Cas9-based engineering of the epigenome

Determining causal relationships between distinct chromatin features and gene expression, and ultimately cell behavior, remains a major challenge. Recent developments in targetable epigenome-editing tools enables us to assign direct transcriptional and functional consequences to locus-specific chrom...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Pulecio, Julian, Verma, Nipun, Mejía-Ramírez, Eva, Huangfu, Danwei, Raya, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205890/
https://ncbi.nlm.nih.gov/pubmed/28985525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.09.006
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