IDH1(R132H) is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment

Recurrent heterozygous mutation of isocitrate dehydrogenase 1 gene (IDH1), predominantly resulting in histidine substitution at arginine 132, was first identified in glioma. The biological significance of IDH1(R132H), however, has been controversial, and its prevalent association with glioma remains...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Tiburcio, Patricia D.B., Xiao, Bing, Chai, Yi, Asper, Sydney, Tripp, Sheryl R., Gillespie, David L., Jensen, Randy L., Huang, L. Eric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2018
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205547/
https://ncbi.nlm.nih.gov/pubmed/30416682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26203
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller