Nalaganje...

The prognostic IDH1(R132) mutation is associated with reduced NADP(+)-dependent IDH activity in glioblastoma

Somatic mutations in the isocitrate dehydrogenase 1 gene (IDH1) occur at high frequency in gliomas and seem to be a prognostic factor for survival in glioblastoma patients. In our set of 98 glioblastoma patients, IDH1 (R132) mutations were associated with improved survival of 1 year on average, afte...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Bleeker, Fonnet E., Atai, Nadia A., Lamba, Simona, Jonker, Ard, Rijkeboer, Denise, Bosch, Klazien S., Tigchelaar, Wikky, Troost, Dirk, Vandertop, W. Peter, Bardelli, Alberto, Van Noorden, Cornelis J. F.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841753/
https://ncbi.nlm.nih.gov/pubmed/20127344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0645-6
Oznake: Označite
Brez oznak, prvi označite!