Mutational profiling of kinases in glioblastoma

BACKGROUND: Glioblastoma is a highly malignant brain tumor for which no cure is available. To identify new therapeutic targets, we performed a mutation analysis of kinase genes in glioblastoma. METHODS: Database mining and a literature search identified 76 kinases that have been found to be mutated...

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Detalhes bibliográficos
Main Authors: Bleeker, Fonnet E, Lamba, Simona, Zanon, Carlo, Molenaar, Remco J, Hulsebos, Theo JM, Troost, Dirk, van Tilborg, Angela A, Vandertop, W Peter, Leenstra, Sieger, van Noorden, Cornelis JF, Bardelli, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192443/
https://ncbi.nlm.nih.gov/pubmed/25256166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-718
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