Noncanonical autophagy at ER exit sites regulates procollagen turnover

Type I collagen is the main component of bone matrix and other connective tissues. Rerouting of its procollagen precursor to a degradative pathway is crucial for osteoblast survival in pathologies involving excessive intracellular buildup of procollagen that is improperly folded and/or trafficked. W...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Omari, Shakib, Makareeva, Elena, Roberts-Pilgrim, Anna, Mirigian, Lynn, Jarnik, Michal, Ott, Carolyn, Lippincott-Schwartz, Jennifer, Leikin, Sergey
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205486/
https://ncbi.nlm.nih.gov/pubmed/30287488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814552115
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