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Deletion of Tmtc4 activates the unfolded protein response and causes postnatal hearing loss

Hearing loss is a significant public health concern, affecting over 250 million people worldwide. Both genetic and environmental etiologies are linked to hearing loss, but in many cases the underlying cellular pathophysiology is not well understood, highlighting the importance of further discovery....

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Li, Jiang, Akil, Omar, Rouse, Stephanie L., McLaughlin, Conor W., Matthews, Ian R., Lustig, Lawrence R., Chan, Dylan K., Sherr, Elliott H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205388/
https://ncbi.nlm.nih.gov/pubmed/30188326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97498
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