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Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane

Gene therapy, used to achieve functional recovery from sensorineural deafness, promises to grant better understanding of the underlying molecular and genetic mechanisms that contribute to hearing loss. Introduction of vectors into the inner ear must be done in a way that widely distributes the agent...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Akil, Omar, Rouse, Stephanie L., Chan, Dylan K., Lustig, Lawrence R.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401361/
https://ncbi.nlm.nih.gov/pubmed/25867531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52187
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