Factor XII activation promotes platelet consumption in the presence of bacterial-type long-chain polyphosphate in vitro and in vivo

OBJECTIVE: Terminal complications of bacterial sepsis include development of disseminated intravascular consumptive coagulopathy. Bacterial constituents, including long-chain polyphosphates (polyP), have been shown to activate the contact pathway of coagulation in plasma. Recent work shows that acti...

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Detaylı Bibliyografya
Yayımlandı:Arterioscler Thromb Vasc Biol
Asıl Yazarlar: Zilberman-Rudenko, Jevgenia, Reitsma, Stephanie E., Puy, Cristina, Rigg, Rachel A., Smith, Stephanie A., Tucker, Erik I., Silasi, Robert, Merkulova, Alona, McCrae, Keith R., Maas, Coen, Urbanus, Rolf T., Gailani, David, Morrissey, James H., Gruber, András, Lupu, Florea, Schmaier, Alvin H., McCarty, Owen J. T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205188/
https://ncbi.nlm.nih.gov/pubmed/30354195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311193
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