In vivo roles of factor XII

Coagulation factor XII (FXII, Hageman factor, EC = 3.4.21.38) is the zymogen of the serine protease, factor XIIa (FXIIa). FXII is converted to FXIIa through autoactivation induced by “contact” to charged surfaces. FXIIa is of crucial importance for fibrin formation in vitro, but deficiency in the pr...

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Bibliographic Details
Main Authors: Renné, Thomas, Schmaier, Alvin H., Nickel, Katrin F., Blombäck, Margareta, Maas, Coen
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507141/
https://ncbi.nlm.nih.gov/pubmed/22993391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-292094
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