Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis

OBJECTIVE: Nuclear receptors are known to regulate both immune and barrier functions in the GI tract. The nuclear orphan receptor NR2F6 has been shown to suppress the expression of proinflammatory cytokines in T lymphocytes. NR2F6 gene expression is reduced in patients with IBS or UC, but its functi...

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Vydáno v:Gut
Hlavní autoři: Klepsch, Victoria, Gerner, Romana R, Klepsch, Sebastian, Olson, William J, Tilg, Herbert, Moschen, Alexander R, Baier, Gottfried, Hermann-Kleiter, Natascha
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2018
Témata:
Inflammatory Bowel Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204953/
https://ncbi.nlm.nih.gov/pubmed/28779026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313466
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