Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9

The caspase recruitment domain–containing protein 9 (CARD9)–B-cell lymphoma/leukemia 10 (Bcl10) signaling axis is activated in myeloid cells during the innate immune response to a variety of diverse pathogens. This signaling pathway requires a critical caspase recruitment domain (CARD)–CARD interact...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Holliday, Michael J., Ferrao, Ryan, de Leon Boenig, Gladys, Estevez, Alberto, Helgason, Elizabeth, Rohou, Alexis, Dueber, Erin C., Fairbrother, Wayne J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204897/
https://ncbi.nlm.nih.gov/pubmed/30206119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004821
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