Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice

Estrogens provide neuroprotection in animal models of stroke, but uterotrophic effects and cancer risk limit translation. Classic estrogen receptors (ERs) serve as transcription factors, whereas nonnuclear ERs govern numerous cell processes and exert beneficial cardiometabolic effects without uterin...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Selvaraj, Uma Maheswari, Zuurbier, Kielen R, Whoolery, Cody W, Plautz, Erik J, Chambliss, Ken L, Kong, Xiangmei, Zhang, Shanrong, Kim, Sung Hoon, Katzenellenbogen, Benita S, Katzenellenbogen, John A, Mineo, Chieko, Shaul, Philip W, Stowe, Ann M
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203892/
https://ncbi.nlm.nih.gov/pubmed/30256928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00600
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