Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice

Estrogens provide neuroprotection in animal models of stroke, but uterotrophic effects and cancer risk limit translation. Classic estrogen receptors (ERs) serve as transcription factors, whereas nonnuclear ERs govern numerous cell processes and exert beneficial cardiometabolic effects without uterin...

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Publicat a:Endocrinology
Autors principals: Selvaraj, Uma Maheswari, Zuurbier, Kielen R, Whoolery, Cody W, Plautz, Erik J, Chambliss, Ken L, Kong, Xiangmei, Zhang, Shanrong, Kim, Sung Hoon, Katzenellenbogen, Benita S, Katzenellenbogen, John A, Mineo, Chieko, Shaul, Philip W, Stowe, Ann M
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203892/
https://ncbi.nlm.nih.gov/pubmed/30256928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00600
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