Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice

Estrogens provide neuroprotection in animal models of stroke, but uterotrophic effects and cancer risk limit translation. Classic estrogen receptors (ERs) serve as transcription factors, whereas nonnuclear ERs govern numerous cell processes and exert beneficial cardiometabolic effects without uterin...

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發表在:Endocrinology
Main Authors: Selvaraj, Uma Maheswari, Zuurbier, Kielen R, Whoolery, Cody W, Plautz, Erik J, Chambliss, Ken L, Kong, Xiangmei, Zhang, Shanrong, Kim, Sung Hoon, Katzenellenbogen, Benita S, Katzenellenbogen, John A, Mineo, Chieko, Shaul, Philip W, Stowe, Ann M
格式: Artigo
語言:Inglês
出版: Endocrine Society 2018
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203892/
https://ncbi.nlm.nih.gov/pubmed/30256928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00600
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