Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice

Steroid hormone receptors including estrogen receptors (ER) classically function as ligand-regulated transcription factors. However, estrogens also elicit cellular effects through binding to extra-nuclear ER (ERα, ERβ, and G protein-coupled ER or GPER) that are coupled to kinases. How extra-nuclear...

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Publicat a:J Mol Cell Cardiol
Autors principals: Menazza, Sara, Sun, Junhui, Appachi, Swathi, Chambliss, Ken L., Kim, Sung Hoon, Aponte, Angel, Khan, Sohaib, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Shaul, Philip W., Murphy, Elizabeth
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514412/
https://ncbi.nlm.nih.gov/pubmed/28457941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.04.004
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