Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

Despite the major negative impact uterine fibroids (UFs) have on female reproductive health, little is known about early events that initiate development of these tumors. Somatic fibroid-causing mutations in mediator complex subunit 12 (MED12), the most frequent genetic alterations in UFs (up to 85%...

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Detaylı Bibliyografya
Yayımlandı:Biol Reprod
Asıl Yazarlar: Prusinski Fernung, Lauren E, Yang, Qiwei, Sakamuro, Daitoku, Kumari, Alpana, Mas, Aymara, Al-Hendy, Ayman
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203880/
https://ncbi.nlm.nih.gov/pubmed/29688260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioy097
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