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A Preliminary Study: Human Fibroid Stro-1(+)/CD44(+) Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1(+)/CD44(+) Cells

CONTEXT: Although uterine fibroids (UFs) continue to place a major burden on female reproductive health, the mechanisms behind their origin remain undetermined. Normal myometrial stem cells may be transformed into tumor-initiating stem cells, causing UFs, due to unknown causes of somatic mutations i...

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Detalhes bibliográficos
Publicado no:Reprod Sci
Main Authors: Prusinski Fernung, Lauren E., Al-Hendy, Ayman, Yang, Qiwei
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728578/
https://ncbi.nlm.nih.gov/pubmed/29954254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719118783252
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