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Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells
Despite the major negative impact uterine fibroids (UFs) have on female reproductive health, little is known about early events that initiate development of these tumors. Somatic fibroid-causing mutations in mediator complex subunit 12 (MED12), the most frequent genetic alterations in UFs (up to 85%...
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| Udgivet i: | Biol Reprod |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6203880/ https://ncbi.nlm.nih.gov/pubmed/29688260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioy097 |
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