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Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

Despite the major negative impact uterine fibroids (UFs) have on female reproductive health, little is known about early events that initiate development of these tumors. Somatic fibroid-causing mutations in mediator complex subunit 12 (MED12), the most frequent genetic alterations in UFs (up to 85%...

詳細記述

保存先:
書誌詳細
出版年:Biol Reprod
主要な著者: Prusinski Fernung, Lauren E, Yang, Qiwei, Sakamuro, Daitoku, Kumari, Alpana, Mas, Aymara, Al-Hendy, Ayman
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203880/
https://ncbi.nlm.nih.gov/pubmed/29688260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioy097
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