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Oncogenic potential of BEX4 is conferred by Polo-like kinase 1-mediated phosphorylation

The brain-expressed X-linked 4 (BEX4) gene has been recently identified as a mediator of microtubule hyperacetylation through sirtuin 2 inhibition and is highly overexpressed in human cancers. However, the gain-of-function molecular mechanism of the BEX4 gene in human cancers still needs to be eluci...

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Pubblicato in:Exp Mol Med
Autori principali: Lee, Jin-Kwan, Ha, Geun-Hyoung, Kim, Hyun-Soo, Lee, Chang-Woo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203768/
https://ncbi.nlm.nih.gov/pubmed/30367032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0168-0
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