Cocaine self-administration alters transcriptome-wide responses in the brain’s reward circuitry

BACKGROUND: Global changes in gene expression underlying circuit and behavioral dysregulation associated with cocaine addiction remain incompletely understood. Here, we show how a history of cocaine self-administration (SA) “re-programs” transcriptome-wide responses throughout the brain’s reward cir...

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Bibliografski detalji
Izdano u:Biol Psychiatry
Glavni autori: Walker, Deena M., Cates, Hannah M., Loh, Yong-Hwee E., Purushothaman, Immanuel, Ramakrishnan, Aarthi, Cahill, Kelly M., Lardner, Casey K., Godino, Arthur, Kronman, Hope G., Rabkin, Jacqui, Lorsch, Zachary S., Mews, Philipp, Doyle, Marie A., Feng, Jian, Labonté, Benoit, Koo, Ja Wook, Bagot, Rosemary C., Logan, Ryan W., Seney, Marianne L., Calipari, Erin S., Shen, Li, Nestler, Eric J.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202276/
https://ncbi.nlm.nih.gov/pubmed/29861096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.04.009
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