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Upregulation and release of soluble fms-like tyrosine kinase receptor 1 (sFLT1) mediated by complement activation in human syncytiotrophoblast cells

PROBLEM: Antiangiogenic molecule sFLT1 released from trophoblast cells is associated with pregnancy specific hypertensive disorder preeclampsia. Cause of elevated sFLT1 in preeclampsia patients is not well understood. Despite evidence of excess systemic and placental complement activation in preecla...

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Detalles Bibliográficos
Publicado en:Am J Reprod Immunol
Main Authors: Banadakoppa, Manu, Balakrishnan, Meena, Yallampalli, Chandra
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202180/
https://ncbi.nlm.nih.gov/pubmed/30099798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.13033
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