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Upregulation and release of soluble fms-like tyrosine kinase receptor 1 (sFLT1) mediated by complement activation in human syncytiotrophoblast cells
PROBLEM: Antiangiogenic molecule sFLT1 released from trophoblast cells is associated with pregnancy specific hypertensive disorder preeclampsia. Cause of elevated sFLT1 in preeclampsia patients is not well understood. Despite evidence of excess systemic and placental complement activation in preecla...
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| Publié dans: | Am J Reprod Immunol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6202180/ https://ncbi.nlm.nih.gov/pubmed/30099798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.13033 |
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