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Cytoplasmic amplification of transcriptional noise generates substantial cell-to-cell variability
Transcription is an episodic process characterized by probabilistic bursts; but how the transcriptional noise from these bursts is modulated by cellular physiology remains unclear. Using simulations and single-molecule RNA counting, we examined how cellular processes influence cell-to-cell variabili...
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| Published in: | Cell Syst |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6202163/ https://ncbi.nlm.nih.gov/pubmed/30243562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.08.002 |
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