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A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization
Diverse biological systems utilize fluctuations (‘noise’) in gene-expression to drive lineage-commitment decisions. However, once a commitment is made, noise becomes detrimental to reliable function, and the mechanisms enabling post-commitment noise suppression are unclear. Here, we find that archit...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044448/ https://ncbi.nlm.nih.gov/pubmed/29754821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.04.005 |
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